MTHR Factor is a physician-formulated dietary supplement designed to support healthy methylation pathways and promote optimal homocysteine metabolism. This advanced blend features highly bioavailable forms of B vitamins—including methylated B12 and folate—for maximum absorption and efficacy. MTHR Factor is especially beneficial for individuals with genetic variations in the MTHFR gene, which can impair the conversion of folate to its active form.

MTHR Factor contains a synergistic blend of activated B vitamins, including folate as Quatrefolic® (5-MTHF) and vitamin B12 as methylcobalamin, to bypass common genetic obstacles to methylation. These nutrients help regulate the methylation cycle, a critical process in DNA repair, detoxification, neurotransmitter production, and cardiovascular health.

• Methylation deficiencies
• Elevated homocysteine levels
• Fatigue and low energy
• Mood imbalances
• Detoxification support
• Nutrient absorption issues related to MTHFR mutations

• Supports healthy methylation and gene expression
• Promotes normal homocysteine metabolism
• Boosts cellular energy production
• Supports brain function and mood regulation
• Contains active, bioavailable B vitamins

MTHR Factor is ideal for individuals who:

• Have or suspect an MTHFR gene mutation
• Want to support cardiovascular, neurological, and detox pathways
• Experience chronic fatigue or mood fluctuations
• Seek a high-quality B vitamin complex with active forms

Always consult a healthcare provider before starting any new supplement, especially if pregnant, nursing, or taking medication.

Take 1 capsule daily with food, or as directed by your healthcare practitioner. Do not exceed recommended dose without professional guidance.

† Daily Value not established.
Other Ingredients: Hypromellose (natural vegetable capsule), microcrystalline cellulose, magnesium stearate, stearic acid, calcium silicate, and silicon dioxide.

Studies have shown that methylated forms of folate and B12 are more efficiently utilized by the body, especially in individuals with MTHFR polymorphisms. Supplementation with these nutrients has been linked to improved homocysteine regulation and enhanced energy and mental clarity.

MTHR Factor is generally well-tolerated. In rare cases, high doses of methylated B vitamins may cause mild side effects such as:

• Headaches
• Restlessness or irritability
• Gastrointestinal discomfort

If any symptoms persist or worsen, discontinue use and consult a healthcare provider.

Q. What makes MTHR Factor different from a regular B complex?
A. MTHR Factor uses methylated forms of folate (5-MTHF) and B12 (methylcobalamin), which are active and better absorbed, especially for those with MTHFR gene mutations.

Q. Can I take MTHR Factor without knowing my MTHFR status?
A. Yes. Methylated B vitamins benefit most people and pose no risk when used appropriately. However, we recommend consulting a provider for personalized advice.

Q. Is this safe during pregnancy?
A. Consult your OB/GYN before using this product if you are pregnant or planning to conceive.

Q. How long before I feel results?
A. Some users experience improvements in energy, focus, and mood within 1–2 weeks. Results may vary based on individual health status.